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Title Selective forces for the origin of spliceosomes Author info Matej Vesteg, Zuzana Šándorová, Juraj Krajčovič Author Vesteg Matej 1982- (60%)
Co-authors Šándorová Zuzana (20%)
Krajčovič Juraj (20%)
Source document Journal of Molecular Evolution. Vol. 74, no. 3-4 (2012), pp. 226-231. - New York : Springer, 2012 Keywords biochémia - biochemistry molekulárna biológia - molekulová biológia - molecular biology evolučná biológia - evolutionary biology Language English Country United States of America systematics 577 Annotation It has been proposed that eukaryotic spliceosomes evolved from bacterial group II introns via constructive neutral changes. However, a more likely interpretation is that spliceosomes and group II introns share a common undefined RNA ancestor—a proto-spliceosome. Although, the constructive neutral evolution may have probably played some roles in the development of complexity including the evolution of modern spliceosomes, in fact, the origin, losses and the retention of spliceosomes can be explained straight-forwardly mainly by positive and negative selection: (1) proto-spliceosomes evolved in the RNA world as a mechanism to excise functional RNAs from an RNA genome and to join noncoding information (ancestral to exons) possibly designed to be degraded. (2) The complexity of proto-spliceosomes increased with the invention of protein synthesis in the RNP world and theywere adopted for (a) the addition of translation signal to RNAs via trans-splicing, and for (b) the exon-shuffling such as to join together exons coding separate protein domains, to translate themas a single unit and thus to facilitate the molecular interaction of protein domains needed to be assembled to functional catalytic complexes. (3) Finally, the spliceosomes were adopted for cis-splicing of (mainly) non-coding information (contemporary introns) to yield translatable mRNAs. (4) Spliceosome-negative organisms (i.e., prokaryotes) have been selected in the DNA–protein world to save a lot of energy. (5) Spliceosome-positive organisms (i.e., eukaryotes) have been selected, because they have been completely spliceosome-dependent Public work category ADC No. of Archival Copy 42335 Repercussion category VOSSEBERG, Julian - SNEL, Berend. Domestication of self-splicing introns during eukaryogenesis : the rise of the complex spliceosomal machinery. In Biology direct. ISSN 1745-6150, 2017, vol. 12, no. 30.
MCNAIR, Jytte Brender - DENNIS, Lynnclaire - KAUFFMAN, Louis H. Mereon matrix, the: Everything connected through (k)nothing. In Mereon Matrix, the : everything connected through (K)nothing. [Singapore] : World scientific publishing, 2018. ISBN 978-981323356-0, pp. 1-846.
MILANOWSKI, Rafal - KARNKOWSKA, Anna - ISHIKAWA, Takao - ZAKRYS, Bozena. Distribution of conventional and nonconventional introns in tubulin (alpha and beta) genes of euglenids. In Molecular biology and evolution. ISSN 0737-4038, 2014, vol. 31, no. 3, pp. 584-593.
DENNIS, L. - MCNAIR, J. Brender - REID, J. S. Dedication to Dr. Robert W. "Bob" Gray. In Mereon matrix : everything connected through (k)nothing. ISSN 0219-9769, 2018, vol. 62, pp. V-+.
PENNY, David - COLLINS, Lesley J. - DALY, Toni K. - COX, Simon J. The relative ages of Eukaryotes and Akaryotes. In Journal of molecular evolution. ISSN 0022-2844, 2014, vol. 79, no. 5-6, special issue, pp. 228-239.
IRIMIA, Manuel - ROY, Scott William. Origin of spliceosomal introns and alternative splicing. In Cold spring harbor perspectives in biology. ISSN 1943-0264, 2014, vol. 6, no. 6, pp. 1-24.
ISOMOTO, Nana - MAEDA, Yuri - TANAKA, Takahiro - FURUTA, Hiroyuki - IKAWA, Yoshiya. Fixation and accumulation of thermotolerant catalytic competence of a pair of ligase ribozymes through complex formation and cross ligation. In Journal of molecular evolution. ISSN 0022-2844, 2013, vol. 76, no. 1-2, pp. 48-58.
DENNIS, L. Preface observational evidence, mathematical verification and inimitable grace. In Mereon matrix : unity, perspective and paradox. Amsterdam : Elsevier, 2013. ISBN 978-0-12-404688-7, pp. XIX-+.
STOLTZFUS, Arlin. Constructive neutral evolution : exploring evolutionary theory's curious disconnect. In Biology direct. ISSN 1745-6150, 2012, vol. 7, art. no. 35, pp. 1-13.
MUSTAFIN, R. N. Basic mechanisms of the origin and evolution of protein-coding genes. In Uspekhi fiziologicheskikh nauk. ISSN 0301-1798, 2020, vol. 51, no. 4, pp. 64-81.
Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ References PERIODIKÁ-Súborný záznam periodika 
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Title Inovatívne prístupy vo výučbe biochémie v pregraduálnej príprave učiteľov prostredníctvom IKT Par.title The Innovative ICT Approaches in Biochemistry Education in the Field of Pregradual Teacher’s Training Author info Marek Skoršepa, Jarmila Kmeťová Author Skoršepa Marek 1976- (50%) UMBFP08 - Katedra chémie
Co-authors Kmeťová Jarmila 1975- (50%) UMBFP08 - Katedra chémie
Source document Media4u Magazine : mimořádné vydání. Roč. 7, X3 (2010), s. 58-63. - Praha : Media4u Magazine, 2010 Keywords biochémia - biochemistry vyučovanie chémie informačné a komunikačné technológie - IKT (informačno-komunikačné technológie) - information and communication technologies - ICT (information and communication technology) Language Slovak Country Czech Republic systematics 54 Public work category ADE No. of Archival Copy 20412 Repercussion category TOMAŠKINOVÁ, Judita - RÁKAIOVÁ, Monika. Improvement of key competences in the context of education for sustainable life through the "FIT model". In INTED 2014 : 8th International technology, education and development conference, March 10th - 12th, Valencia (Spain) 2014, conference proceedings. 1. vyd. Valencia : IATED, 2014. ISBN 978-84-616-8412-0. ISSN 2340-1079, s. 3786-3792.
Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ unrecognised
Title Veterinárska farmakológia Subtitle špeciálna časť Document part 1. diel Author info rec. Jozef Bíreš, Štefan Šimko Another authors Bíreš Jozef (Recenzent)
Šimko Štefan 1942- (Recenzent)
Issue data Košice : Univerzita veterinárskeho lekárstva , 2008. - 225 s. Issue 1. vyd. ISBN 978-80-8077-102-7 Keywords veterinárska farmakológia veterinárne lekárstvo anatómia histológia biochémia - biochemistry infekčné ochorenia diagnostika a terapia Language Slovak Country Slovak Republic systematics 61 Public work category FAI Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ 
book
Title Biochemické experimentálne metódy Par.title Biochemical experimental methods Author info Marek Skoršepa, Dagmar Vaculčíková, Kamil Cejpek Author Skoršepa Marek 1976- (80%) UMBFP08 - Katedra chémie
Co-authors Vaculčíková Dagmar (10%) UMBFP08 - Katedra chémie
Cejpek Kamil (10%) UMBFP08 - Katedra chémie
Issue data Banská Bystrica : Fakulta prírodných vied , 2008. - 203 s. ISBN 978-80-8083-570-5 Keywords biochémia - biochemistry experimentálne metódy - experimental methods Language Slovak Country Slovak Republic systematics 577.1(075.8) Annotation Vysokoškolské skriptá predstavujúce súhrn návodov experimentov zo základných principiálnych metód experimentálnej biochémie určených na laboratórne cvičenia z biochémie na FPV UMB. Jednotlivé témy sú nasledovné: aminokyseliny a bielkoviny, sacharidy, lipidy, enzýmy, rastlinné pigmenty, vitamíny, praktická biochémia (mlieko, moč, alkaloidy, kvasenie, hormóny) Public work category BCI No. of Archival Copy 10155 Repercussion category KUBÁT, Václav et al. Modulární systém dalšího vzdělávávní pedagogických pracovníků v chemii. In Súčasnosť a perspektívy didaktiky chémie III. : medzinárodná konferencia, Donovaly, 29. - 31. 5. 2013. Banská Bystrica : Univerzita Mateja Bela v Banskej Bystrici, 2013. ISBN 978-80-557-0546-0, s. 174-177.
Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ unrecognised
Title Sedemdesiat rokov docenta Ivana Ružičku Author info Milan Melicherčík, Kamil Cejpek Author Melicherčík Milan 1948-2015 UMBFP08 - Katedra chémie
Co-authors Cejpek Kamil UMBFP08 - Katedra chémie
Source document Acta Universitatis Matthiae Belii, No 8 - Séria chémia. S. 12-14. - Banská Bystrica, 2004 : Univerzita Mateja Bela / Tölgyessy Juraj ; Tomeček Otto 1934-2004 ; Melicherčík Milan 1948-2015 ; Cejpek Kamil Note Fot. Person keywords Ružička Ivan Keywords životné jubileá biochémia - biochemistry Language Slovak Country Slovak Republic systematics 929 Public work category GII No. of Archival Copy 4873 Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ 
article
Title Synergetická interpretácia liečby dysfunkcie sínusového uzla prostredníctvom kardiostimulácie Author info Ján Červeň, Miroslava Červeňová, Miroslav Tuma Author Červeň Ján
Co-authors Červeňová Miroslava
Tuma Miroslav 1931- UMBFP08 - Katedra chémie
Source document 53. zjazd chemických spoločností : Zborník príspevkov 3. Sekcie F, I, J, M. Banská Bystrica, 3.- 6. september 2001. S. 338-339. - Banská Bystrica : Univerzita Mateja Bela, 2001 Keywords kardiostimulácia dysfunkcie myokard biochémia - biochemistry systematics 577.1:611.12 Public work category AFJ Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ unrecognised
Title Zaujímavosti degradácie hemoglobínu Author info Marek Skoršepa, Jarmila Kmeťová Author Skoršepa Marek 1976- (90%) UMBFP08 - Katedra chémie
Co-authors Kmeťová Jarmila 1975- (10%) UMBFP08 - Katedra chémie
Source document 53. zjazd chemických spoločností : zborník príspevkov, Banská Bystrica, 3.- 6. september 2001, Č. 1, sekcie E, L, N . S. 186-187. - Banská Bystrica : Univerzita Mateja Bela, 2001 Keywords biochémia - biochemistry hemoglobín degradácia Language Slovak Country Slovak Republic systematics 577.1 Public work category AFD Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ unrecognised
Title Biochémia 1 Subtitle skriptá pre poslucháčov nadstavbového štúdia Author info Ján Karabelly Author Karabelly Ján 1969- UMBFP08 - Katedra chémie
Issue data Banská Bystrica : Stredné odborné učilište poľnohospodársko-potravinárske , 1995. - 61 s. Keywords biochémia - biochemistry skriptá stredoškolské texty - texts Language Slovak Country Slovak Republic systematics 547:37(075.4) Public work category BCI Catal.org. UKUMB###UK UMB###BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ book