(5S)-5-Benzylswainsonines as potent and selective inhibitors of Golgi α-mannosidase II: synthesis, enzyme evaluation and molecular modelling

KALNÍK, Martin - GABKO, Peter - KÓŇA, Juraj - ŠESTÁK, Sergej - MONCOL, Ján - BELLA, Maroš. (5S)-5-Benzylswainsonines as potent and selective inhibitors of Golgi α-mannosidase II: synthesis, enzyme evaluation and molecular modelling. In Bioorganic chemistry, 2024, vol. 150, art. no. 107578. ISSN 0045-2068. Dostupné na: https://doi.org/10.1016/j.bioorg.2024.107578
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:[1.1] KOEMANS, T. - BENNETT, M. - FERRAZ, M.J. - ARMSTRONG, Z. - ARTOLA, M. - AERTS, J.M.F.G. - CODEE, J.D.C. - OVERKLEEFT, H.S. - DAVIES, G.J. Structure-guided design of C3-branched swainsonine as potent and selective human Golgi α-mannosidase (GMII) inhibitor. In CHEMICAL COMMUNICATIONS. ISSN 1359-7345, OCT 10 2024, vol. 60, no. 82, p. 11734-11737. Dostupné na: https://doi.org/10.1039/d4cc04514a., Registrované v: WOS
:[1.1] WAN, A.J. - FOO, J.B. - LOO, J.S.E. Uncovering the potential of the anchor site for enhancing Golgi alpha-mannosidase II selectivity using molecular dynamics simulations and free energy calculations. In JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. ISSN 0739-1102, SEP 2 2025, vol. 43, no. 13, p. 7190-7198. Dostupné na: https://doi.org/10.1080/07391102.2025.2475223., Registrované v: WOS