Výsledky vyhľadávania
Názov Euglena gracilis and trypanosomatids possess common patterns in predicted mitochondrial targeting presequences Aut.údaje Katarína Krnáčová ... [et al.] Autor Krnáčová Katarína (40%)
Spoluautori Vesteg Matej 1982- (30%)
Hampl Vladimír (5%)
Vlček Čestmír (5%)
Horváth Anton (20%)
Zdroj.dok. Journal of Molecular Evolution. Vol. 75, no. 3-4 (2012), pp. 119-129. - New York : Springer, 2012 Kľúč.slová červenoočká - Euglenoids - Euglenida genómy - genomes kinetoplastidy - kinetoplastids molekulárna fylogenetika - molecular phylogenetics Jazyk dok. angličtina Systematika 577 Anotácia Euglena gracilis possessing chloroplasts of secondary green algal origin and parasitic trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania major belong to the protist phylum Euglenozoa. Euglenozoa might be among the earliest eukaryotic branches bearing ancestral traits reminiscent of the last eukaryotic common ancestor (LECA) or missing features present in other eukaryotes. LECA most likely possessed mitochondria of endosymbiotic alpha-proteobacterial origin. In this study, we searched for the presence of homologs of mitochondria-targeted proteins from other organisms in the currently available EST dataset of E. gracilis. The common motifs in predicted N-terminal presequences and corresponding homologs from T. brucei, T. cruzi and L. major (if found) were analyzed. Other trypanosomatid mitochondrial protein precursor (e. g., those involved in RNA editing) were also included in the analysis. Mitochondrial presequences of E. gracilis and these trypanosomatids seem to be highly variable in sequence length (5-118 aa), but apparently share statistically significant similarities. In most cases, the common (M/L)RR motif is present at the N-terminus and it is probably responsible for recognition via import apparatus of mitochondrial outer membrane. Interestingly, this motif is present inside the predicted presequence region in some cases. In most presequences, this motif is followed by a hydrophobic region rich in alanine, leucine, and valine. In conclusion, either RR motif or arginine-rich region within hydrophobic aa-s present at the N-terminus of a preprotein can be sufficient signals for mitochondrial import irrespective of presequence length in Euglenozoa. URL Link do databázy WoS Kategória publikačnej činnosti ADC Číslo archívnej kópie 37274 Kategória ohlasu FURUHASHI, Takeshi - OGAWA, Takumi - NAKAI, Rai - NAKAZAWA, Masami - OKAZAWA, Atsushi - PADERMSCHOKE, Adchara - NISHIO, Kazuki - HIRAI, Masami Yokota - ARITA, Masanori - OHTA, Daisaku. Wax ester and lipophilic compound profiling of Euglena gracilis by gas chromatography-mass spectrometry: toward understanding of wax ester fermentation under hypoxia. In Metabolomics. ISSN 1573-3882, 2015, vol. 11, no. 1, pp. 175-183.
MANTILLA, Brian S. - PAES, Lisvane S. - PRAL, Elizabeth M. F. - MARTIL, Daiana E. - THIEMANN, Otavio H. - FERNANDEZ-SILVA, Patricio - BASTOS, Erick L. - SILBER, Ariel M. Role of Delta(1)-Pyrroline-5-Carboxylate Dehydrogenase supports mitochondrial metabolism and host-cell invasion of trypanosoma cruzi. In Journal of biological chemistry. ISSN 0021-9258, 2015, vol. 290, no. 12, pp. 7767-7790.
TAMAKI, Shun - MARUTA, Takanori - SAWA, Yoshihiro - SHIGEOKA, Shigeru - ISHIKAWA, Takahiro. Biochemical and physiological analyses of NADPH-dependent thioredoxin reductase isozymes in Euglena gracilis. In Plant science. ISSN 0168-9452, 2015, vol. 236, pp. 29-36.
MARTINEZ-GARCIA, Marta - CAMPOS-SALINAS, Jenny - CABELLO-DONAYRE, Maria - PINEDA-MOLINA, Estela - GALVEZ, Francisco J. - ORREGO, Lina M. - SANCHEZ-CANETE, Maria P. - MALAGARIE-CAZENAVE, Sophie - KOELLER, David M. - PEREZ-VICTORIA, Jose M. LmABCB3, an atypical mitochondrial ABC transporter essential for Leishmania major virulence, acts in heme and cytosolic iron/sulfur clusters biogenesis. In Parasites & vectors. ISSN 1756-3305, 2016, vol. 9, art. no. 7.
ZIMORSKI, Verena - RAUCH, Cessa - VAN HELLEMOND, Jaap J. - TIELENS, Aloysius G.M. - MARTIN, William F. The mitochondrion of Euglena gracilis. In Advances in experimental medicine and biology. ISSN 0065-2598, 2017, no. 979, pp. 19-37.
IVANOVA, Irina M. - NEPOGODIEV, Sergey A. - SAALBACH, Gerhard - O'NEILL, Ellis C. - URBANIAK, Michael D. - FERGUSON, Michael A. J. - GURCHA, Sudagar S. - BESRA, Gurdyal S. - FIELD, Robert A. Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes. In Carbohydrate research. ISSN 0008-6215, 2017, vol. 438, pp. 26-38.
KUHAUDOMLARP, Sakonwan - PATRON, Nicola J. - HENRISSAT, Bernard - REJZEK, Martin - SAALBACH, Gerhard - FIELD, Robert A. Identification of Euglena gracilis β-1,3-glucan phosphorylase and establishment of a new glycoside hydrolase (GH) family GH149. In Journal of biological chemistry. ISSN 0021-9258, 2018, vol. 293, no. 8, pp. 2865-2876.
JARDIM, Armando - HARDIE, Darryl B. - BOITZ, Jan - BORCHERS, Christoph H. Proteomic profiling of leishmania donovani promastigote subcellular organelles. In Journal of proteome research. ISSN 1535-3893, 2018, vol. 17, no. 3, pp. 1194-1215.
BANDINI, Giulia - DAMEROW, Sebastian - GUTHER, Maria Lucia Sempaio - GUO, Hongjie - MEHLERT, Angela - FRANCO, Jose Carlos Paredes - BEVERLEY, Stephen - FERGUSON, Michael A. J. An essential, kinetoplastid-specific GDP-Fuc: beta-D-Gal alpha-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei. In eLife. ISSN 2050-084X, 2021, vol. 10, art. no. e70272, pp. 1-27.
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